Your Cart is Empty
What it is
Designed for
Patients stay relaxed. Providers stay in control
Nitronox Plus Nitrous Oxide & Oxygen System
1
The Nitronox Plus Nitrous Oxide and Oxygen System by Porter Instrument is a safe, easy-to-use regulator that delivers a controlled mix of oxygen and nitrous oxide—commonly known as laughing gas....
What it is
Designed for
Patients stay relaxed. Providers stay in control
Designed to improve comfort and profitability
Adjustable Control 0–70%
Nitronox offers adjustable levels—start lower for sensitive patients or increase for greater relief, unlike fixed 50/50 systems like Pro-Nox™
Lower Patient Dropouts
You work hard—and spend a lot—to get patients in the door. If pain keeps them from completing their treatment plan, you lose revenue you already paid to acquire. Enhancing comfort helps ensure patients stay, finish, and return
100% Oxygen Flush
Delivers 100% oxygen post-treatment to flush residual nitrous—supporting faster recovery. Fixed 50/50 systems like Pro-Nox™ don’t offer this
Lower Liability
Prescribing sedatives means coordinating rides, longer recovery times, and increased liability. Nitrous oxide wears off within minutes, allowing patients to return to normal activities quickly—without the added operational risk
New Revenue Stream
Nitronox doesn’t just improve treatments—it generates revenue. Offering nitrous oxide as a paid upgrade helps the system pay for itself while adding recurring income to your practice
Stay Competitive
Nitrous oxide is quickly becoming a standard offering. Practices that provide it position themselves as more advanced, more patient-focused, and more appealing than those that don’t
NITRONOX PLUS vs PRO-NOX™*
Compare the features that matter most
Nitronox Plus
Adjustable comfort, designed for modern practices- Adjustable 0-70% nitrous oxide & oxygen mixture
- Dedicated 100% oxygen flush capability
- Manufactured in the United States
- Security key access for trained users
- On-site repair capability
- No yearly device recalibration required
- No factory recalibration cost
- 3-year warranty
- Mounted on a rolling stand
- FDA registered
- Built-in hypoxia prevention system
- Automatic shut-off when not in use or if pressure drops
PRO-NOX™*
Fixed-ratio nitrous delivery- Fixed 50/50 nitrous oxide & oxygen mixture
- Does not include a dedicated 100% oxygen flush capability
- Manufactured outside of the United States
- Does not include security key access for trained users
- Does not support on-site repairs
- Requires yearly device recalibration
- Factory recalibration cost of $1,190
- 2-year warranty
- Mounted on a rolling stand
- FDA registered
- Built-in hypoxia prevention system
- Automatic shut-off when not in use or if pressure drops
Comfort = revenue protection
Painful procedures cost you more than you think
Patient Anxiety
Patients cancel or avoid painful procedures
Treatment Dropouts
Patients don’t complete full treatment plans
Sedatives & Liability
Patients can’t drive home
Hidden Costs
Topicals & meds add up
SAFETY & CONFIDENCE
Trusted patient comfort solution
Proven Safety
Long history of clinical use
Conscious Sedation Patients remain awake and responsive
Lower Liability
No deep sedation or driving concerns
Fast Recovery
Oxygen flush post-treatment
• Transient dizziness or lightheadedness
• Mild nausea or queasiness
• Headache
• Tingling or warm sensation
• Short-lived altered sensation (e.g., tingling or floating feeling)
• Effects resolve quickly after discontinuation
• Known or suspected pneumothorax (collapsed lung)
• Significant pulmonary disease with air trapping (e.g., COPD with bullae)
• Bowel obstruction or other conditions with trapped air spaces
• Decompression sickness (recent SCUBA diving)
• Severe vitamin B12 deficiency (risk of inactivation by nitrous oxide)
• Altered level of consciousness or inability to self-administer (unable to hold mask)
• Pregnancy (early trimester) or obstetric considerations per clinician judgment
Regulator Dimensions:
11” x 11” x 8” (28cm x 28cm x 20.3cm) Weight: 13 lbs (5.9 kg)
Tank Type:
• Uses standard “E” cylinder or "E" Type Tank
• Available from medical gas suppliers
• At normal breathing rates, gas supply will last approximately:
• N₂O: 6 hours
• O₂: 2 hours
Gas Supply Pressure:
• O₂: 45 to 60 psi (310.3 to 413.6 kPa)
• N₂O: 45 to 60 psi (310.3 to 413.6 kPa)
Alarm Activation:
• Whistle alarm signals a low gas supply when the pressure drops to approximately 35 psi (2.41 bar)
ROI CALCULATOR
See how Nitronox Plus pays for itself
Your Practice Inputs
$
Your Estimated Results
Monthly Revenue $0
Monthly Costs $0
Monthly Profit $0
Payoff time 0 months
We offer competitive financing options
See Real Medical Aesthetics Practice Example Below
Monthly Device Payment
$225
Competitive interest rate
Monthly Revenue
$3,000
20 x $150 per session
Consumables + Gas
$500
$25 per session
Monthly Profit
$2,250
Revenue - Costs
✓ Paid Off Early
"We were in need of an anesthesia device, specifically NO2 delivery, for our more uncomfortable procedures. Speaking with Medical Spa Supply was informative and refreshing. They educated me about the Nitronox; their communication was prompt and efficient, and they quickly arranged financing with very reasonable terms. I highly recommend Medical Spa Supply for any Med Spa needs, and we are proud to call them a partner in our success."
Why Practices Choose Medical Spa Supply for Nitronox Plus?
More than a distributor — a long-term partner in your practice’s success
#1 Distributor Nationwide
The leading Nitronox distributor for aesthetics and medical wellness practices in the U.S.
Trusted Industry Partner
We provide expert guidance to help practices implement nitrous oxide with confidence
Best-in-Class Service
From consultation to ongoing support, our team is responsive and knowledgeable
Training & Patient Brochures Included
Each purchase includes complimentary staff training and patient brochures that explain benefits, outline side effects, and increase treatment acceptance
Medical Aesthetics
OB-GYN Birthing Centers
FAQs
Questions & Answers
Have a Question?
-
Can an RN administer nitrous oxide in our practice?
In most cases, medical clinicians like RN's can administer nitrous oxide and oxygen using a system like Nitronox Plus, as long as it falls within their professional scope of practice. While there may not be a specific regulation that names nitrous oxide directly, its use is generally considered part of minimal sedation, analgesia, or anxiolysis—similar to administering a local anesthetic. The key is that the treating clinician must ensure it aligns with their state’s practice guidelines and that proper training, protocols, and medical oversight are in place. If your license allows you to administer medications for mild sedation or pain relief, you are likely eligible to use Nitronox Plus in your practice. Always check with your state regulatory boards to confirm it is permitted within your scope of practice.
Still have questions?
×
Nitronox Breathing Circuit & Mouthpiece Bundle - Request Info
Medical Spa Supply is here to help your practice thrive. Our account managers take a consultative, no-pressure approach to help you find the right solution—simply share a few details and we’ll provide a tailored quote.