September 03, 2026 4 min read
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Before many aesthetic procedures, patients ask the same question:
“Is this going to hurt?”
For treatments such as microneedling, dermal fillers, and laser procedures, an effective numbing protocol can help ease that concern and create a more comfortable patient experience.
The challenge is that traditional compounded numbing creams can add unnecessary complexity. Prescription requirements, refrigeration, storage protocols, and sourcing considerations all create extra steps for your practice.Nonprescription options such as NeuroMed BLT and Zensa offer a simpler way to support patient comfort.
Many practices use compounded BLT cream, a customized combination of benzocaine, lidocaine, and tetracaine prepared by a compounding pharmacy.
While these formulations may be appropriate for certain procedures, they can introduce additional operational considerations:
Fortunately, compounded BLT is not the only option available.
NeuroMed BLT, from Sambria Pharmaceuticals combines benzocaine, lidocaine, and tetracaine in individually packaged, single-use components.
It offers practices a convenient way to incorporate a three-anesthetic numbing system without managing patient-specific prescriptions or refrigerated inventory.

Each 5g or 10g dose contains three separate packets:
| Component | Active Ingredient | Intended role |
|---|---|---|
| NeuroMedFA | 20% Benzocaine | Rapid onset with a shorter duration |
| NeuroMed7 | 4% Lidocaine | Medium onset and duration |
| NeuroMedLA | Tetracaine | Rapid onset with an extended duration |
How NeuroMed BLT is used:
NeuroMed BLT is intended for single-patient use. Any unused mixture should be discarded rather than stored for a future procedure.
Available in two sizes, depending on the surface area you're treating.
Not every procedure requires a three-anesthetic system.
For practices looking for a straightforward, ready-to-use option, Zensa Numbing Cream contains 5% lidocaine in a water-based formula. There are no separate components to mix, making it easy to incorporate into a busy treatment schedule.
How Zensa is used:
Recommended application time can vary depending on the treatment, treatment area, skin condition, and individual patient response. Always refer to the product instructions before use.

Zensa is sold as a single tube or in bulk, with per-tube pricing dropping as volume increases — from $34 for one tube down to $26 per tube at 48 units.
| Compounded BLT | NeuroMed BLT | Zensa | |
|---|---|---|---|
| Prescription required | Yes | No | No |
| Refrigeration required | Yes | No | No |
| Cost per 3 mL (facial treatment) | $6-$11 | $4.99 (5 mL packet) | $4.33 (when purchasing 48 tubes) |
| Sourcing requirement | For bulk/general use, must come from a 503B outsourcing facility (not a 503A pharmacy) | Ships directly, no special sourcing | Ships directly, no special sourcing |
| Format | Custom-mixed | 3 packets, mixed at time of use | Single ready-to-use cream |
| Active ingredients | Benzocaine, lidocaine, tetracaine | Benzocaine, lidocaine, tetracaine | Lidocaine 5% |
| Best for | Practices needing a customized BLT formulation that can manage compliance requirements. | Practices that want BLT-without the compliance overhead | Practices that want a simpler, single-step numbing option |
NeuroMed BLT may be a good fit when you want a three-ingredient numbing system for more involved treatment protocols, without adding prescription management or refrigerated storage.
Zensa may be the better choice when simplicity is the priority. Its single-formula application makes it easy to stock, prepare, and incorporate into a wide range of treatment workflows.
Some practices may choose to keep both available, using the appropriate option based on the procedure, treatment area, and patient’s needs.
Whichever product you select, it should be supported by clear staff training, consistent application protocols, appropriate patient screening, and careful adherence to the manufacturer’s instructions.
Looking for a simpler approach to patient comfort?
Medical Spa Supply can help you compare NeuroMed BLT and Zensa based on your procedures, treatment volume, and preferred workflow.
Contact our team to find the right numbing option for your practice.
Product information is provided for general educational purposes and is not a substitute for clinical judgment, manufacturer instructions, or applicable federal and state requirements. Verify current product directions, pricing, availability, and regulations before use.
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