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Home / Products / Porter Nitronox Plus Nitrous Oxide & Oxygen Analgesia Systems
Porter New Nitronox® Plus Demand Flow Nitrous Oxide & Oxygen Analgesia Systems
Nitronox Plus 0-70% Adjustable (NOX-PLUS-070)
Nitronox Plus 0-50 NOX-PLUS-050
Nitronox Plus 50/50 Fixed NOX-PLUS-5050

Porter Nitronox Plus Nitrous Oxide & Oxygen Analgesia Systems

Porter Instrument - Nitronox

NOX-PLUS-070-2NS

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Porter Nitronox Plus Nitrous Oxide & Oxygen Analgesia Systems - Request Info

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Porter New Nitronox® Plus Demand Flow Nitrous Oxide & Oxygen Analgesia Systems
Nitronox Plus 0-70% Adjustable (NOX-PLUS-070)
Nitronox Plus 0-50 NOX-PLUS-050
Nitronox Plus 50/50 Fixed NOX-PLUS-5050

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At Medical Spa Supply, our mission is to provide equipment, supplies, and business solutions to Med Spa and Medical Esthetics partners that help their businesses thrive. One such solution is our Best Price Guarantee. We want you and your staff to feel confident that you’re purchasing products at the best possible price. We help you eliminate wasted time shopping around and comparing prices, so you have more time to grow your business. If you see an item advertised somewhere for less, please chat, call, or email us prior to placing your order and we will match most delivered prices on the same item in the continental US. Please note we will not price match items listed on Ebay / other auction websites or from companies that violate the manufacturer's minimum advertised pricing policies.

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Increase patient comfort while boosting your revenue

The Nitronox Plus Nitrous Oxide and Oxygen System by Porter Instrument is a safe and easy-to-use regulator that delivers a mix of oxygen and nitrous oxide, commonly known as laughing gas. It provides fast-acting, short-term relief from pain and anxiety during medical aesthetic and medical procedures. With over 50 years of proven reliability, Nitronox helps patients stay comfortable during procedures like microneedling, dermal fillers, Ultherapy, laser tattoo removal, and other medical treatments that can cause discomfort. Because the effects wear off quickly, patients can resume their day with little to no downtime.

Benefits to Your Practice:

  • Complete procedures more efficiently
  • Reduced recovery time and liability for patient monitoring
  • Decrease "treatment dropout"
  • Increase revenue by charging for nitrous oxide
How much revenue can you earn for your business? Contact Us 

Safety/acceptance

Nitrous oxide and oxygen (N2O/O2) provides a safe, simple, and fast-acting alternative to oral medications for minimal sedation. During the procedure, patients experience a reduction in pain and anxiety due to the analgesic and anxiolytic properties of N2O. After the procedure, the effects on the patient wear off within minutes.

0-70% Adjustable Nitrous Oxide 

Competitive systems are limited to delivering a fixed 50/50 mix of nitrous oxide and oxygen, which may not be suitable for all patients. With Nitronox Plus, you control the nitrous oxide mix to match each patient’s needs. Start low and adjust up for those sensitive to nitrous, or provide higher levels for patients needing more relief—all while ensuring a smooth, comfortable experience.
Plus, at the end of the procedure, a 100% oxygen flush helps clear the system, something fixed 50/50 systems can’t do.

Comfortable with a maximum of 50% nitrous oxide, no problem! Choose from three models tailored to your needs:
  • 0-70% adjustable nitrous oxide (NOX-PLUS-070-2NS)
  • 0-50% adjustable (NOX-PLUS-050-2NS)
  • 50/50% fixed system (NOX-PLUS-5050-2NS)

Which model will work best for your practice? Feel free to chat or call us at (800) 880-8260 if you need assistance—an expert in nitrous oxide delivery systems is here to help!

Demand flow system with enhanced safety features:

• Available in fixed or adjustable mixture concentration models
• Key lock mechanism for safety and security
• Audible low gas pressure alarm
• Internal but accessible demand valve that never requires recalibration
• Safety function test button

Designed to meet infection prevention standards:

• One-way directional flow of inhaled and exhaled gas
• Single-use, disposable breathing circuits
• Single-use masks and mouthpieces
• Front panel user interfaces designed to prevent surface cleaners and disinfectants from entering the device

Each unit comes with a 2-cylinder cart

Dimensions: 11” x 11” x 8” (28cm x 28cm x 20.3cm)
Weight: 13 lbs (5.9 kg)

Connection Fittings:
• Oxygen Inlet: DISS 1240 (Male)
• Nitrous Oxide Inlet: DISS 1040A (Male)
• Mixed Gas Connection Port: 22 mm taper

Gas Supply Pressure:
• O2: 45 to 60 psi (310.3 to 413.6 kPa)
• N2O: 45 to 60 psi (310.3 to 413.6 kPa)

Temperature:
• Storage & Transportation: -40°F to 140°F (-40°C to 60°C)
• Operational: 41°F to 100°F (5°C to 38°C)

Humidity:
• Storage & Transportation: 10-70%
• Operational: 10-70%

Atmospheric Pressure: 1 atm ± 0.2 atm (101 kPa ± 20 kPa)

Mixture Settings: Preset 50% N2O/O2 (50/50 model)

Delivery Flowrate: Up to 100 L/min total flow at 50% N2 O/O2

Delivery Accuracy:
• Normal and Heavy Breathing: ± 5% O2
• Light/Shallow Breathing: +20/-5% O2

Usage Time, With “E” Cylinders at normal breathing rates, gas supply, will last approximately:
• N2O: 6 hours
• O2: 2 hours

Alarm Activation: Whistle alarm signals a low gas supply when the pressure drops to approximately 35 psi (2.41 bar)

Demand Valve: Cracking Pressure: < 2 cmH2O

3 Year manufacturer warranty

Porter Instrument is the foremost authority in nitrous oxide equipment and is renowned for its Nitronox Plus system. As the leader in nitrous oxide sedation systems for the Med Spa/aesthetic medicine and medline wellness markets, Porter Instrument has been manufacturing the highest quality medical equipment since its establishment in 1968. A commitment to precision and safety and a legacy of innovation and quality make Nitronox Plus the go-to choice for medical nitrous oxide analgesia systems.

Demand flow system with enhanced safety features:

• Available in fixed or adjustable mixture concentration models
• Key lock mechanism for safety and security
• Audible low gas pressure alarm
• Internal but accessible demand valve that never requires recalibration
• Safety function test button

Designed to meet infection prevention standards:

• One-way directional flow of inhaled and exhaled gas
• Single-use, disposable breathing circuits
• Single-use masks and mouthpieces
• Front panel user interfaces designed to prevent surface cleaners and disinfectants from entering the device

Each unit comes with a 2-cylinder cart

Dimensions: 11” x 11” x 8” (28cm x 28cm x 20.3cm)
Weight: 13 lbs (5.9 kg)

Connection Fittings:
• Oxygen Inlet: DISS 1240 (Male)
• Nitrous Oxide Inlet: DISS 1040A (Male)
• Mixed Gas Connection Port: 22 mm taper

Gas Supply Pressure:
• O2: 45 to 60 psi (310.3 to 413.6 kPa)
• N2O: 45 to 60 psi (310.3 to 413.6 kPa)

Temperature:
• Storage & Transportation: -40°F to 140°F (-40°C to 60°C)
• Operational: 41°F to 100°F (5°C to 38°C)

Humidity:
• Storage & Transportation: 10-70%
• Operational: 10-70%

Atmospheric Pressure: 1 atm ± 0.2 atm (101 kPa ± 20 kPa)

Mixture Settings: Preset 50% N2O/O2 (50/50 model)

Delivery Flowrate: Up to 100 L/min total flow at 50% N2 O/O2

Delivery Accuracy:
• Normal and Heavy Breathing: ± 5% O2
• Light/Shallow Breathing: +20/-5% O2

Usage Time, With “E” Cylinders at normal breathing rates, gas supply, will last approximately:
• N2O: 6 hours
• O2: 2 hours

Alarm Activation: Whistle alarm signals a low gas supply when the pressure drops to approximately 35 psi (2.41 bar)

Demand Valve: Cracking Pressure: < 2 cmH2O

3 Year manufacturer warranty

Porter Instrument is the foremost authority in nitrous oxide equipment and is renowned for its Nitronox Plus system. As the leader in nitrous oxide sedation systems for the Med Spa/aesthetic medicine and medline wellness markets, Porter Instrument has been manufacturing the highest quality medical equipment since its establishment in 1968. A commitment to precision and safety and a legacy of innovation and quality make Nitronox Plus the go-to choice for medical nitrous oxide analgesia systems.

FAQs

Is the Nitronox® Plus nitrous oxide and oxygen system safe?

How fast does nitrous oxide take effect and last?

How much can my practice charge for Nitrious Oxide?

Does nitrous oxide eliminate pain?

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Questions & Answers

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  • Can an RN administer nitrous oxide in our practice?

    In most cases, medical clinicians like RN's can administer nitrous oxide and oxygen using a system like Nitronox Plus, as long as it falls within their professional scope of practice. While there may not be a specific regulation that names nitrous oxide directly, its use is generally considered part of minimal sedation, analgesia, or anxiolysis—similar to administering a local anesthetic. The key is that the treating clinician must ensure it aligns with their state’s practice guidelines and that proper training, protocols, and medical oversight are in place. If your license allows you to administer medications for mild sedation or pain relief, you are likely eligible to use Nitronox Plus in your practice. Always check with your state regulatory boards to confirm it is permitted within your scope of practice.

  • How do you prevent Diffusion hypoxia when on demand is used and therefore the patient is not receiving 100% oxygen administration after nitrous oxide cessation?

    This is one huge benefit of Nitronox Plus. It can deliver 100% oxygen by either turning the knob to 0% nitrous or turning the key to the off position. For that reason, we fully recommend doing that at the end of every procedure.